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Data associated with selected splice site

Sequence

 atgc   intronic sequence     ATGC   exonic sequence

CCAGAGAATACTGTCGGTGTTCTGACAATGGCAGGTAAAGGCCCACGAGTTCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatctcttgaattgcatatggccttacttttgggtgctctattgtcattctttttagtactttttttttccaatcatttgcaatggacgtatgtggactgggtggagtatctgaagaggctggtgtacacttcattctttcttgatatatggtgttttactag

Basic information

species Physcomitrella patens
transcript PP1S14_318V6.1
intron # 3
splice site 5'
intron type U2

Mapped EST sequences

Showing partial alignments of ESTs and genomic sequences. See full alignments


 ATGC     EST sequence
 ATGC     genomic sequence (exon)
 ATGC     genomic sequence (truncated intron)


EST: gi|100381151|gb|BY950004.1|BY950004
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100410542|gb|BY992154.1|BY992154
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100424156|gb|BY958342.1|BY958342
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|162235944|gb|FC411687.1|FC411687
EST:     GATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: GATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67709869|gb|BJ965685.1|BJ965685
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67719536|gb|BJ969795.1|BJ969795
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18372410|gb|BJ204012.1|BJ204012
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|162159573|gb|FC335751.1|FC335751
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18366328|gb|BJ198407.1|BJ198407
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100399854|gb|BY990655.1|BY990655
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100359179|gb|BY965630.1|BY965630
EST:     TCTTATCACTCCAACCAACGACTTGGNAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18344610|gb|BJ176651.1|BJ176651
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100422820|gb|BY958017.1|BY958017
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|162270585|gb|FC446510.1|FC446510
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100361055|gb|BY946891.1|BY946891
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100444272|gb|BY982301.1|BY982301
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67703411|gb|BJ963644.1|BJ963644
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGAT
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGAT
EST: gi|100426210|gb|BY958783.1|BY958783
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100414734|gb|BY956837.1|BY956837
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67710256|gb|BJ965919.1|BJ965919
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100390114|gb|BY989194.1|BY989194
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67702739|gb|BJ962972.1|BJ962972
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100410928|gb|BY956252.1|BY956252
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100449851|gb|CJ973968.1|CJ973968
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18331986|gb|BJ163998.1|BJ163998
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GNTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGA
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGA
EST: gi|67719741|gb|BJ970000.1|BJ970000
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18343869|gb|BJ175907.1|BJ175907
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18357197|gb|BJ189256.1|BJ189256
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67569334|gb|BJ942158.1|BJ942158
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100449557|gb|CJ973819.1|CJ973819
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|208361374|gb|DC930371.1|DC930371
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100436137|gb|BY979398.1|BY979398
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAGGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|162195399|gb|FC370868.1|FC370868
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67716301|gb|BJ966561.1|BJ966561
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100353224|gb|BY945668.1|BY945668
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100400831|gb|BY972965.1|BY972965
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|100381386|gb|BY950102.1|BY950102
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18375025|gb|BJ206603.1|BJ206603
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|67717273|gb|BJ967532.1|BJ967532
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
EST: gi|18326030|gb|BJ158029.1|BJ158029
EST:     TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATG                         GTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC
genomic: TCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTC

RNA-Seq data


 ATGC   Supported by RNA-Seq exonic block that spans over the splice site

 atgs   Truncated intron sequence

Each block is as long as the maximal overhang of any read spanning the junction.
The score is the number of alignments spanning the junction.


Found data for 1 RNA-Seqlibrary.


Block sizes: 31 (upstream exon), 30 (downstream exon)
Score: 9

CCAGAGAATACTGTCGGTGTTCTGACAATGGCAGGTAAAGGCCCACGAGTTCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatc ... gttttactagGTTTGGAAGTTGGGGGCGAGATGCGTATGACATCGGGAGTTCAAGTTGCTCAGCTAGCGTTGAAGCATCGCCAGAACAAGCATCAGCGACAGAGAATTGT




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Putative cis-regulatory sequences

 atgc intron ATGC exonic elements by Pertea et al.
 ATGC exon atgc putative intronic elements
 ATGC putative exonic elements identified for retained introns
        10        20        30        40        50        60        70        80        90        100       110       120       130       140       150       160       170       180       190       200       210       220 
---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------| 
CCAGAGAATACTGTCGGTGTTCTGACAATGGCAGGTAAAGGCCCACGAGTTCTTATCACTCCAACCAACGACTTGGGAAAGATCCTCCAAGCTCTTCATGgtatgccatctcttgaattgcatatggccttacttttgggtgctctattgtcattctttttagtactttttttttccaatcatttgcaatggacgtatgtggactgggtggagtatctgaagaggctggtgtacacttcattctttcttgatatatggtgttttactag

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -  CAAGCT