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Data associated with selected splice site

Sequence

 atgc   intronic sequence     ATGC   exonic sequence

gtatcgcctgcaccttgctgggaaatcatgtttttagtaattcgaatcattatgttggtttcgtatattttctgtatccaaaacaataacctgaaacactacgaagtatatgatcctagcacatttctgaacgaattaatctgtttttaaccttgctttgacttgggtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG

Basic information

species Zea mays
transcript GRMZM2G162461_T01
intron # 13
splice site 3'
intron type U2

Orthologous splice sites


 atgc   intronic sequence     ATGC   exonic sequence


upper sequence: GRMZM2G162461_T01 (Zea mays), 3'ss of exon 13
lower sequence: LOC_Os10g03400.2 (Oryza sativa), 3'ss of exon 12
---gtatcgcctgcaccttgctgg----gaaatcatgtttttagtaattcgaatcattatgtt---ggtttcgtatat-tttctgtatcc---aaaacaataacctgaaacactacgaagtatatgatcc---tagcacatttctgaacgaattaatctgtttttaaccttgctttgacttgggtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG------
      | |  |||||||| |||      | | |||  || |   | | | ||   |||||||     |   || |||   |||  ||||   | | |  ||   | |||      ||     |  |      |       | ||   |  | ||| |  ||| |||        ||   |  ||  ||  || |||||||||||||||||||||| ||   ||||||| | ||||||||||||||||| ||||| |  ||       
gtgagtttgtttgcaccttactgatgataagaacattattattacattaccaaagtttatgttttaattcctgtgtatacatcttaatcccatagatcggtattattaaatgtgttgagactaacaaattatatgttgttctactattcttactaaaccatttctaaaacacgcctgttatatgttcttttagGCCTTGCAGGAGACTCTTGAGCGACAAGAGGAGATCATGGCATACATTGAGAAGAAAAAGAAGAAGAAAAGCAAG

upper sequence: GRMZM2G162461_T01 (Zea mays), 3'ss of exon 13
lower sequence: LOC_Os02g24430.2 (Oryza sativa), 3'ss of exon 12
gtatcgcctgcaccttgctgggaaatcatgtttttagta-attcgaatcattatgttggtttcgtatattttctgtatccaaaacaataac-ctgaaacactacgaagtatatgatcctagcacatttctgaacgaattaatctgtttttaaccttgctttgacttgggtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG------
|| | | |||       ||     || ||      || | ||||   | ||||  ||  |  | || || |    |||  ||   | | |  || | | | |||     || |  | |||  ||  ||       | | || |  || | || |  || |    |  | | ||| ||| |||||||||||||||||||||| ||   ||||||| | ||||||||||||||||| ||||| |  ||       
gt-ttgtctgttttcaccttaatgatgata-----agcacattc---ttattacattaatcccatagatctgtattattaaatgtattgagactaacaaattac-----atgttgttctactactctt-------actaaaccatttctaaaacacgcatattatatgtttttttcagGCCTTGCAGGAGACTCTTGAGCGGCAAGAGGAGATCATGGCATACATTGAGAAGAAAAAGAAGAAGAAAAGCAAG
















Mapped EST sequences

Showing partial alignments of ESTs and genomic sequences. See full alignments


 ATGC     EST sequence
 ATGC     genomic sequence (exon)
 ATGC     genomic sequence (truncated intron)


EST: gi|14311498|gb|BG901253.1|BG901253
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|8102787|gb|AW927468.1|AW927468
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870569|gb|CF010251.1|CF010251
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|7135744|gb|AW498243.1|AW498243
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         GCCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870385|gb|CF010067.1|CF010067
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870542|gb|CF010224.1|CF010224
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|6918395|gb|AW399925.1|AW399925
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870512|gb|CF010194.1|CF010194
EST:     CTGTCTCCCGCGTTAGTGCCCTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATCCATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870274|gb|CF009956.1|CF009956
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|8102786|gb|AW927467.1|AW927467
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870513|gb|CF010195.1|CF010195
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870386|gb|CF010068.1|CF010068
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870675|gb|CF010357.1|CF010357
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|21390916|gb|BQ528965.1|BQ528965
EST:     GAAGAGGAGC-TGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: GAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870275|gb|CF009957.1|CF009957
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|21390754|gb|BQ528803.1|BQ528803
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|91050815|gb|EB161233.1|EB161233
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|6918678|gb|AW400208.1|AW400208
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|14255699|gb|BG878607.1|BG878607
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32870497|gb|CF010179.1|CF010179
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATCCATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|14311611|gb|BG901366.1|BG901366
EST:     TCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: TCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|71422239|gb|DR805663.1|DR805663
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|78091380|gb|DV519754.1|DV519754
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTGGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|7137803|gb|AW499278.1|AW499278
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|211223043|gb|FL464247.1|FL464247
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|32869242|gb|CF008924.1|CF008924
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|8382999|gb|BE056047.1|BE056047
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
EST: gi|71422238|gb|DR805662.1|DR805662
EST:     CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAG                         ACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG
genomic: CTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAG

RNA-Seq data


 ATGC   Supported by RNA-Seq exonic block that spans over the splice site

 atgs   Truncated intron sequence

Each block is as long as the maximal overhang of any read spanning the junction.
The score is the number of alignments spanning the junction.


Found data for 3 RNA-Seq libraries.


Block sizes: 42 (upstream exon), 49 (downstream exon)
Score: 14

GACAAAACCCGCATCAATGCCTGCTGATAAGGAGGAGGTTCTGCAGGCTGCTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG


Block sizes: 29 (upstream exon), 21 (downstream exon)
Score: 1

GACAAAACCCGCATCAATGCCTGCTGATAAGGAGGAGGTTCTGCAGGCTGCTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG


Block sizes: 49 (upstream exon), 44 (downstream exon)
Score: 325

GACAAAACCCGCATCAATGCCTGCTGATAAGGAGGAGGTTCTGCAGGCTGCTGTCTCCCGCGTTAGTGCACTGGAAGAGGAGCTTGCAGCTACAAAGAAGgtatcgcctg ... gtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG




 atgc   intronic sequence     ATGC   exonic sequence

Intronic sequence truncated to 55 bases.

catttctgaacgaattaatctgtttttaaccttgctttgacttgggtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG
                                              tctttgc  CT-rich tract
            aattaatctgttttta  TA-rich tract
















Putative cis-regulatory sequences

 atgc intron ATGC exonic elements by Pertea et al.
 ATGC exon atgc putative intronic elements
 ATGC putative exonic elements identified for retained introns
        10        20        30        40        50        60        70        80        90        100       110       120       130       140       150       160       170       180       190       200       210       220 
---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------|---------| 
gtatcgcctgcaccttgctgggaaatcatgtttttagtaattcgaatcattatgttggtttcgtatattttctgtatccaaaacaataacctgaaacactacgaagtatatgatcctagcacatttctgaacgaattaatctgtttttaaccttgctttgacttgggtctttgcagACCTTGCAGGAGACTCTTGAGCGTCAGTTGGAGATCGTTGCATACATTGAGAAGAAGAAGAAAAGCAAG

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -  TTGGAG
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - TGGAGA
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -  GGAGAT
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - GAGATC
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -  AAGAAG
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - AAGAAG
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -  AAGAAA
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - AAGCAA
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -  AGCAAG